Osteoarthritis can be modeled in mice by destabilization with the medial meniscus by surgically sectioning a ligament inside the joint. The CB2 receptor agonist HU308 diminished joint injury while in the DMM osteoarthritis design, While CB2 (−/−) mice developed much more joint problems than wild- style mice (Sophocleous et al, https://mylesxirma.sharebyblog.com/32655252/5-essential-elements-for-tetrahydrocannabinol-thc