Induction of microsomal enzymes by this drug, might shorten the 50 percent-life of doxycycline for so long as two weeks following barbiturate therapy discontinued; monitor medical response to doxycycline closely if the two drugs administered concurrently pentobarbital will lessen the extent or impact of theophylline by impacting hepatic/intestinal enzyme CYP3A4 https://pentobarbital46253.therainblog.com/33074323/considerations-to-know-about-nembutal-drug