BACKGROUND/ABSTRACT: Immune responses initiated by T cell receptor (TCR) and costimulatory molecule mediated signaling culminate in maximal cytokine mRNA production and stability. The transcriptional responses to co-stimulatory T cell signalling involve calcineurin and NF-AT. which can be antagonized by interference with the cis-trans peptidyl-prolyl isomerases (PPIase). cyclophilin A... https://www.jmannino.com/quick-offer-Viqua-F4-50-Plus-Monitored-UV-System-Powered-by-UVMax-15-gpm-230-Volt-on-sale/