Pentobarbital will decrease the level or effect of fentanyl transdermal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Closely. Coadministration of fentanyl with CYP3A4 inducers could lead to a decrease Per mezzo di fentanyl plasma concentrations, lack of efficacy or, possibly, development of a withdrawal syndrome Per mezzo di a https://tetrabookmarks.com/story20334852/la-guida-definitiva-a-pentobarbital-half-life